The arena was first named Everblades Arena in 1998 after the hockey team that played there. TECO Energy was the first company to obtain the naming rights to the building, changing the name to TECO Arena. In 2004, TECO Energy decided they were no longer interested in holding the naming rights. Germain Motor Company bought the rights, and in 2004 the venue was renamed to Germain Arena. This same company, an automobile dealership with locations in Florida, Arkansas, and Ohio, also held the naming rights to the Germain Amphitheater in Columbus, Ohio.
Germain Arena has been used as a multipurpose venue, primarily hosting the Florida Everblades ECHL ice hockey team and the Florida Tarpons Ultimate Indoor Football League team. It was also the home for the Florida Flame NBA Development League team and the Florida Firecats Arena Football League 2 (af2) team. Additionally, the venue has hosted various concerts, circuses, boxing, mixed martial arts events, Total Nonstop Action Wrestling house shows, World Wrestling Entertainment house shows and Professional Bull Riders events.
Germain Arena is also home to the Florida Gulf Coast University Eagles Hockey Team of the American Collegiate Hockey Association (ACHA). In March 2006 and March 2010, the facility hosted the Division 3 ACHA National Championships and in March 2008 the Division 2 ACHA National Championships.The arena is scheduled to hold the 2012 Division 2 championship.